As often as people say "life is too short", sometimes it really doesn't register until you reflect back on your life, and realize time didn't stop because of all the good reasons you had for not being where you really want to be.
It keeps flying by and those reasons just keep getting better and better, giving way to new situations to justify with even more reasons. And as comforting as it is to get understanding from others, it doesn't make the burden on your heart any less lighter.
And sooner or later, those reasons become defining and you're walking through life with unwanted credentials attached to your name.
I'm not being sarcastic when I say those reasons are good ones. I have a few of my own. But its worth it to do whatever it takes to overcome them. If it'll give you peace of mind, if it'll make you happy, fulfilled, its totally worth it.
So go after your dream, lose weight, go back to school, go for that career change... Life really is too short to let reasons rule your life. Its up to you to make things happen in spite of them and replace those credentials with the right ones!